Charles Sanders Peirce said this quote

It is the man of science, eager to have his every opinion regenerated, his every idea rationalized, by drinking at the fountain of fact, and devoting all the energies of his life to the cult of truth, not as he understands it, but as he does not yet understand it, that ought properly to be called a philosopher.

~ Charles Sanders Peirce

Upon this first, and in one sense this sole, rule of reason, that in order to learn you must desire to learn, and in so desiring not be satisfied with what you already incline to think, there follows one corollary which itself deserves to be inscribed upon every wall of the city of philosophy: Do not block the way of inquiry.

~ Charles Sanders Peirce

To satisfy our doubts . . . it is necessary that a method should be found by which our beliefs may be determined by nothing human, but by some external permanency -- by something upon which our thinking has no effect. . . . Our external permanency would not be external, in our sense, if it was restricted in its influence to one individual. It must be something which affects, or might affect, every man. And, though these affections are necessarily as various as are individual conditions, yet the method must be such that the ultimate conclusion of every man shall be the same. Such is the method of science. Its fundamental hypothesis, restated in more familiar language, is this: There are Real things, whose characters are entirely independent of our opinions about them; those Reals affect our senses according to regular laws, and, though our sensations are as different as are our relations to the objects, yet, by taking advantage of the laws of perception, we can ascertain by reasoning how things really and truly are; and any man, if he have sufficient experience and he reason enough about it, will be led to the one True conclusion. The new conception here involved is that of Reality.

~ Charles Sanders Peirce

To satisfy our doubts . . . it is necessary that a method should be found by which our beliefs may be determined by nothing human, but by some external permanency -- by something upon which our thinking has no effect. . . . Our external permanency would not be external, in our sense, if it was restricted in its influence to one individual. It must be something which affects, or might affect, every man. And, though these affections are necessarily as various as are individual conditions, yet the method must be such that the ultimate conclusion of every man shall be the same. Such is the method of science. Its fundamental hypothesis, restated in more familiar language, is this: There are Real things, whose characters are entirely independent of our opinions about them; those Reals affect our senses according to regular laws, and, though our sensations are as different as are our relations to the objects, yet, by taking advantage of the laws of perception, we can ascertain by reasoning how things really and truly are; and any man, if he have sufficient experience and he reason enough about it, will be led to the one True conclusion. The new conception here involved is that of Reality. It may be asked how I know that there are any Reals. If this hypothesis is the sole support of my method of inquiry, my method of inquiry must not be used to support my hypothesis. The reply is this: 1. If investigation cannot be regarded as proving that there are Real things, it at least does not lead to a contrary conclusion; but the method and the conception on which it is based remain ever in harmony. No doubts of the method, therefore, necessarily arise from its practice, as is the case with all the others. 2. The feeling which gives rise to any method of fixing belief is a dissatisfaction at two repugnant propositions. But here already is a vague concession that there is some one thing which a proposition should represent. Nobody, therefore, can really doubt that there are Reals, for, if he did, doubt would not be a source of dissatisfaction. The hypothesis, therefore, is one which every mind admits. So that the social impulse does not cause men to doubt it. 3. Everybody uses the scientific method about a great many things, and only ceases to use it when he does not know how to apply it. 4. Experience of the method has not led us to doubt it, but, on the contrary, scientific investigation has had the most wonderful triumphs in the way of settling opinion. These afford the explanation of my not doubting the method or the hypothesis which it supposes; and not having any doubt, nor believing that anybody else whom I could influence has, it would be the merest babble for me to say more about it. If there be anybody with a living doubt upon the subject, let him consider it.

~ Charles Sanders Peirce