Lydia Millet said this quote

Beyond aspects of pain that are physical, thought Oppenheimer, sickness or injury or privation, beyond the so-called obvious, suffering can be a work of art. It can be made of buried and rising things, helpless and undiscovered, song of frustrated want, silence after desire. It can be the test of the self falling short, constrained, distorted, disturbed or rebuffed, the vacuum left by longing, call without an answer.