Thomas C. Oden said this quote

In this sense every serious choice has a tragicomic dimension. For it is impossible to be a human being without choosing, and it is impossible to choose without value denials, and it is impossible to deny values without guilt. That is a very simple though, but it forms the core definition of guilt: an awareness of significant value loss for which I know myself to be responsible. Guilt is the self-knowing of moral loss.

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