These computer simulations try only to duplicate the interactions between the cortex and the thalamus. Huge chunks of the brain are therefore missing. Dr. [Dharmendra] Modha understands the enormity of his project. His ambitious research has allowed him to estimate what it would take to create a working model of the entire human brain, and not just a portion or a pale version of it, complete with all parts of the neocortex and connections to the senses. He envisions using not just a single Blue Gene computer [with over a hundred thousand processors and terabytes of RAM] but thousands of them, which would fill up not just a room but an entire city block. The energy consumption would be so great that you would need a thousand-megawatt nuclear power plant to generate all the electricity. And then, to cool off this monstrous computer so it wouldn't melt, you would need to divert a river and send it through the computer circuits.It is remarkable that a gigantic, city-size computer is required to simulate a piece of human tissue that weighs three pounds, fits inside your skull, raises your body temperature by only a few degrees, uses twenty watts of power, and needs only a few hamburgers to keep it going.
~ Michio Kaku