George Gamow said this quote

“ If and when all the laws governing physical phenomena are finally discovered, and all the empirical constants occurring in these laws are finally expressed through the four independent basic constants, we will be able to say that physical science has reached its end, that no excitement is left in further explorations, and that all that remains to a physicist is either tedious work on minor details or the self-educational study and adoration of the magnificence of the completed system. At that stage physical science will enter from the epoch of Columbus and Magellan into the epoch of the National Geographic Magazine! ”