James Madison said this quote

Every new and successful example, therefore, of a perfect separation between the ecclesiastical and civil matters, is of importance; and I have no doubt that every new example will succeed, as every past one has done, in showing that religion and government will both exist in greater purity the less they are mixed together.

~ James Madison

Religious bondage shackles and debilitates the mind and unfits it for every noble enterprise.... During almost fifteen centuries has the legal establishment of Christianity been on trial. What have been its fruits? More or less, in all places, pride and indolence in the clergy; ignorance and servility in laity; in both, superstition, bigotry, and persecution.

~ James Madison

The advancement and diffusion of knowledge is the only guardian of true liberty.

~ James Madison

In framing a government, which is to be administered by men over men, the great difficulty is this: You must first enable the government to control the governed; and in the next place, oblige it to control itself.

~ James Madison