Mike Birbiglia said this quote

“ When I was starting out, I thought I would go into comedy and there would be a mentor, like the Philip Seymour Hoffman character in 'Almost Famous,' in my life, and there just wasn't. It was really frustrating for me because I desired that so much. ”

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Saturday night is perfect for writers because other people have plans.

~ Mike Birbiglia

...And so we go and I meet his parents. And it's a very strange thing meeting your girlfriend's boyfriend's parents for the first time. Part of you is angry for obvious reasons and part of you still wants to make a good impression. On a side note, they seemed in perfect health.

~ Mike Birbiglia

Bears are simultaneously so graceful and so strong. Bears know who they are, but they often don’t know who you are, which is why they kill you.

~ Mike Birbiglia

I try to think up material that might apply to the subjects they are studying. How many mitochondria does it take to power a cell? One. Because mitochondria are the powerhouse of the cell. Not ready for prime time, that one.

~ Mike Birbiglia