Thus, by science I mean, first of all, a worldview giving primacy to reason and observation and a methodology aimed at acquiring accurate knowledge of the natural and social world. This methodology is characterized, above all else, by the critical spirit: namely, the commitment to the incessant testing of assertions through observations and/or experiments — the more stringent the tests, the better — and to revising or discarding those theories that fail the test. One corollary of the critical spirit is fallibilism: namely, the understanding that all our empirical knowledge is tentative, incomplete and open to revision in the light of new evidence or cogent new arguments (though, of course, the most well-established aspects of scientific knowledge are unlikely to be discarded entirely).. . . I stress that my use of the term 'science' is not limited to the natural sciences, but includes investigations aimed at acquiring accurate knowledge of factual matters relating to any aspect of the world by using rational empirical methods analogous to those employed in the natural sciences. (Please note the limitation to questions of fact. I intentionally exclude from my purview questions of ethics, aesthetics, ultimate purpose, and so forth.) Thus, 'science' (as I use the term) is routinely practiced not only by physicists, chemists and biologists, but also by historians, detectives, plumbers and indeed all human beings in (some aspects of) our daily lives. (Of course, the fact that we all practice science from time to time does not mean that we all practice it equally well, or that we practice it equally well in all areas of our lives.)

~ Alan Sokal

To understand this new frontier, I will have to try to master one of the most difficult and counterintuitive theories ever recorded in the annals of science: quantum physics. Listen to those who have spent their lives immersed in this world and you will have a sense of the challenge we face. After making his groundbreaking discoveries in quantum physics, Werner Heisenberg recalled, I repeated to myself again and again the question: Can nature possibly be so absurd as it seemed to us in these atomic experiments? Einstein declared after one discovery, If it is correct it signifies the end of science. Schrödinger was so shocked by the implications of what he'd cooked up that he admitted, I do not like it and I am sorry I had anything to do with it. Nevertheless, quantum physics is now one of the most powerful and well-tested pieces of science on the books. Nothing has come close to pushing it off its pedestal as one of the great scientific achievements of the last century. So there is nothing to do but to dive headfirst into this uncertain world. Feynman has some good advice for me as I embark on my quest: I am going to tell you what nature behaves like. If you will simply admit that maybe she does behave like this, you will find her a delightful, entrancing thing. Do not keep saying to yourself, if you can possibly avoid it, 'But how can it be like that?' because you will get 'down the drain,' into a blind alley from which nobody has yet escaped. Nobody knows how it can be like that.

~ Marcus Du Sautoy